Friday, April 19, 2024
Weight Loss

Endoscopic Sleeve Gastroplasty Presents Secure, Significant Weight Loss for Sufferers with Class III Weight problems

Sufferers misplaced and maintained greater than 20 p.c of complete physique weight after three years, with medical enchancment in metabolic comorbidities

Endoscopic sleeve gastroplasty (ESG) is an efficient, long-term weight reduction device for sufferers with class III weight problems—resulting in important complete physique weight reduction (TBWL) and extra weight reduction (EWL) after three years, in line with analysis that was chosen for presentation at Digestive Illness Week® (DDW) 2022. Whereas ESG is historically considered as optimum for sufferers with a physique mass index (BMI) beneath 40 kg/m2, findings from this research present that the process can result in important weight reduction and enchancment in metabolic comorbidities in greater BMI sufferers who don’t need or aren’t eligible for conventional bariatric surgical procedure.

Within the largest longitudinal ESG research up to now in sufferers with class III weight problems (outlined as a physique mass index for 40 or greater), greater than 400 sufferers underwent the ESG process at two websites (Cary, North Carolina, and Sao Paulo, Brazil) and had been adopted for as much as three years. Sufferers misplaced 16.5 p.c of their complete physique weight at 6 months; 20.9 p.c at 12 months; 20.5 p.c at 24 months and 20.3 p.c at 36 months.

The analysis additionally demonstrated important enchancment in metabolic comorbidities, with 66 p.c of sufferers with hypertension seeing enchancment simply six months after their ESG process. Equally, 61 p.c of sufferers with kind II diabetes; 52 p.c of sufferers with obstructive sleep apnea; and, 45 p.c of sufferers with hyperlipidemia noticed enchancment or decision of their respective comorbidity.

“We’re in determined want of extra instruments and coverings for sufferers affected by weight problems, particularly at school III, the place the therapy hole stays so massive,” explains Dr. Christopher McGowan, founder and medical director of True You Weight Loss and principal investigator of the research. “We all know that just one p.c of these eligible for bariatric surgical procedure will finally select the surgical path. Non-surgical endobariatric procedures like ESG provide extremely efficient, extraordinarily secure choices for sufferers who wish to get their weight underneath management however aren’t occupied with or eligible for bariatric surgical procedure.”

ESG is carried out endoscopically with the Apollo Overstitch suturing system (Apollo Endosurgery; Austin, TX), with an endoscopist inserting a sequence of operating sutures throughout the abdomen to create a sleeve-like form, lowering the capability of the abdomen by as a lot as 80%, and resulting in earlier satiety. Owing to its non-surgical method, ESG carries a decrease danger of issues and long-term unwanted effects akin to gastroesophageal reflux illness (GERD). On this research, the general adversarial occasion charge was a mere 0.5%, markedly decrease than the complication charge seen with conventional bariatric surgical procedure.

“Given the long-term effectiveness and security of the ESG process in sufferers with class III weight problems as evidenced on this research, ESG must be thought-about an appropriate choice for sufferers with a BMI of 40+ who’re on the lookout for alternate options to bariatric surgical procedure,” mentioned Dr. McGowan. “This process is considerably bettering sufferers’ lives and general well being—with out the numerous danger of issues that comes with having main surgical procedure. We’re so thrilled that we are able to now provide minimally invasive weight reduction procedures that may ship close to surgical degree outcomes.”

DDW Presentation Particulars

Dr. McGowan will current knowledge from the research throughout his presentation titled, “ESG in Class III Weight problems: Weight Loss and Metabolic Outcomes in 404 Consecutive Sufferers” [abstract 3694076] through the “Endoscopic Sleeve Gastroplasty Gastric Plication: The Maturing of a Process” matter discussion board on Tuesday, Might 24, at 10 am PDT.



Digestive Illness Week® (DDW) is the most important worldwide gathering of physicians, researchers and teachers within the fields of gastroenterology, hepatology, endoscopy and gastrointestinal surgical procedure. Collectively sponsored by the American Affiliation for the Examine of Liver Ailments (AASLD), the American Gastroenterological Affiliation (AGA) Institute, the American Society for Gastrointestinal Endoscopy (ASGE) and the Society for Surgical procedure of the Alimentary Tract (SSAT), DDW is an in-person and digital assembly from Might 21-24, 2022. The assembly showcases greater than 3,100 abstracts and a whole bunch of lectures on the most recent advances in GI analysis, medication and know-how. Extra info might be discovered at